Our research is dedicated to bring molecular advances in the pathogenesis and therapy of human brain tumors to clinical application. Our laboratory aims to identify new therapeutic leads for patients with high-grade gliomas and to develop tools that allow predicting an individual patient’s likelihood to benefit from a certain treatment regimen. Our work integrates complex molecular tumor data generated by the complementary and iterative application of data-driven (genome-wide analysis) and hypothesis-driven research approaches and corresponding clinical patient profiles. |